Research & Development News Channel

Non-opioid compounds squelch pain without sedation

A newly identified set of molecules alleviated pain in mice while avoiding the sedating affect that limits the use of opiates, according to a new study led by researchers at UC San Francisco. The molecules act on the same receptor as clonidine and dexmedetomidine - drugs commonly used in hospitals as sedatives - but are chemically unrelated to them and may not be addictive.

Breakthrough brings potential glioblastoma drug into focus

Glioblastoma, the most common cancerous brain tumor in adults, is an aggressive disease - patients survive an average of just 15 months once they are diagnosed. Despite more than two decades of research on the causes and treatments of glioblastoma, that prognosis has hardly improved.

Similar medications cost more for humans compared to pets

In a research letter published in JAMA Internal Medicine, University of Minnesota researchers compared the prices of 120 medications commonly used in humans and pets. The authors found the price of human medications was generally higher than the price of pet medications with the same ingredients at common human-equivalent doses.

National CDC-funded study confirms that mRNA vaccines protect against serious COVID-19 during pregnancy

The first large, real-world study of the effectiveness of mRNA COVID-19 vaccines during pregnancy found these vaccines, especially two initial doses followed by a booster, are effective in protecting against serious disease in expectant mothers whether the shots are administered before or during pregnancy.

2nd Annual Next Generation Pharmaceutical Cleanrooms Conference

5 - 6 October 2022, London, United Kingdom.
SAE Media Group are pleased to announce the 2nd Annual Next Generation Pharmaceutical Cleanroom Conference. An event that focuses on cleanroom technology in the pharmaceutical industry, the conference will serve to bridge that gap between the two areas while simultaneously providing a unique selling point.

Shutting down backup genes leads to cancer remission in mice

The way that tumor cells enable their uncontrolled growth is also a weakness that can be harnessed to treat cancer, researchers at the University of Michigan and Indiana University have shown.

Their machine-learning algorithm can identify backup genes that only tumor cells are using so that drugs can target cancer precisely.

Bird's enzyme points toward novel therapies

Thank the rare crested ibis for a clue that could someday help our bodies make better drugs.

The species of bird is the only one known to naturally produce an enzyme able to generate a noncanonical amino acid; that is, one not among the 20 necessary to encode most proteins.

Research & Development News

Non-opioid compounds squelch pain without sedation

Breakthrough brings potential glioblastoma drug into focus

Similar medications cost more for humans compared to pets

National CDC-funded study confirms that mRNA vaccines protect against serious COVID-19 during pregnancy

2nd Annual Next Generation Pharmaceutical Cleanrooms Conference

Shutting down backup genes leads to cancer remission in mice

Bird's enzyme points toward novel therapies

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