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Undetected coronavirus variant was in at least 15 countries before its discovery

A highly contagious SARS-CoV-2 variant was unknowingly spreading for months in the United States by October 2020, according to a new study from researchers with The University of Texas at Austin COVID-19 Modeling Consortium. Scientists first discovered it in early December in the United Kingdom, where the highly contagious and more lethal variant is thought to have originated.

COVID-19 survivors might need just one dose of two-part vaccine

A single dose of the Pfizer-BioNTech vaccine for individuals who previously had COVID-19 generates an immunologic response similar to that of individuals receiving the two-dose recommended sequence, according to a Cedars-Sinai study published today by the journal Nature Medicine.

B.1.1.7 variant of COVID-19 spreading rapidly in United States

The faster-spreading B.1.1.7 variant of SARS-CoV-2 first detected in the United Kingdom, the coronavirus that causes COVID-19, is quickly on its way to becoming the dominant variant of the virus in the United States, according to a study from scientists at Scripps Research and the COVID-19 test maker Helix.

Anti-inflammatory drug protects against lethal inflammation from COVID-19 in animal models

Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19. In a study published today in the journal Cell, the team reported that the drug, Topotecan (TPT), inhibited the expression of inflammatory genes in the lungs of mice as late as four days after infection, a finding with potential implications for treatment of humans.

Will COVID-19 vaccines need to be adapted regularly?

Influenza vaccines need to be evaluated every year to ensure they remain effective against new influenza viruses. Will the same apply to COVID-19 vaccines? In order to gauge whether and to what extent this may be necessary, a team of researchers from Charité - Universitätsmedizin Berlin compared the evolution of endemic 'common cold' coronaviruses with that of influenza viruses.

Individual SARS-CoV-2 neutralising antibody immunity lasts from days to decades

Scientists from Duke-NUS Medical School, the National Centre for Infectious Diseases (NCID) and the Agency for Science, Technology and Research (A*STAR) Infectious Diseases Labs found that antibodies against SARS-CoV-2 wane at different rates, lasting for mere days in some individuals, while remaining present in others for decades.

Hormone drugs may disarm COVID-19 spike protein and stop disease progression

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.

Research & Development News

Undetected coronavirus variant was in at least 15 countries before its discovery

COVID-19 survivors might need just one dose of two-part vaccine

B.1.1.7 variant of COVID-19 spreading rapidly in United States

Anti-inflammatory drug protects against lethal inflammation from COVID-19 in animal models

Will COVID-19 vaccines need to be adapted regularly?

Individual SARS-CoV-2 neutralising antibody immunity lasts from days to decades

Hormone drugs may disarm COVID-19 spike protein and stop disease progression

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