Research

Autoimmune diseases: discovery of central building block in immune cells

Autoimmune diseases are triggered when the immune system malfunctions and attacks the body's own structures. Although there is not, as yet, any cure for such diseases, their progression can be slowed down by therapeutic measures. Researchers at MedUni Vienna's Center for Physiology and Pharmacology have now discovered a central signaling pathway in immune cells that may help in the development of a new therapeutic approach.

Why natural killer cells react to COVID-19

Little has been known to date about how the immune system's natural killer (NK) cells detect which cells have been infected with SARS-CoV-2. An international team of scientist led by researchers from Karolinska Institutet in Sweden now shows that NK cells respond to a certain peptide on the surface of infected cells.

Study suggests increased risk of mental health disorders after COVID-19 infection

A study published by The BMJ finds that COVID-19 is associated with an increased risk of mental health disorders, including anxiety, depression, substance use, and sleep disorders, up to one year after initial infection.

The findings suggest that tackling mental health disorders among survivors of COVID-19 should be a priority.

Harnessing vaccine technology to heal bone

Although fractures normally heal, bone will not regenerate under several circumstances. When bone does not regenerate, major clinical problems could result, including amputation.

To enhance the regeneration of bone, the Food and Drug Administration (FDA) approved recombinant human bone morphogenetic protein-2, or BMP-2. However, it is expensive and only moderately effective. It also produces side effects - some severe.

New study finds COVID-19 vaccination boosts mental health along with immunity

Getting vaccinated for COVID-19 measurably improved the psychological well-being of participants in the Understanding Coronavirus in America study, a large longitudinal look at the impact of the pandemic on individuals in the United States. Vaccination was associated with declines in distress and perceived risks of infection, hospitalization, and death.

Antibodies improve in quality for months after COVID-19 vaccination

For at least six months after COVID-19 vaccination, antibodies produced by immune cells become steadily more formidable and more precisely targeted against the virus that causes COVID-19, according to a study of the antibody response to the Pfizer-BioNTech vaccine by researchers at Washington University School of Medicine in St. Louis.

Study shows new drug combination more effective against SARS-CoV-2

Researchers at the University of Maryland School of Medicine (UMSOM) and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19. The researchers showed that combining the experimental drug brequinar with either of the two drugs already approved by the U.S. Food and Drug Administration for emergency use, remdesivir or molnupiravir, inhibited growth of the SARS-CoV-2 virus in human lung cells and in mice.

Autoimmune diseases: discovery of central building block in immune cells

Why natural killer cells react to COVID-19

Study suggests increased risk of mental health disorders after COVID-19 infection

Harnessing vaccine technology to heal bone

New study finds COVID-19 vaccination boosts mental health along with immunity

Antibodies improve in quality for months after COVID-19 vaccination

Study shows new drug combination more effective against SARS-CoV-2

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