Virus shows promise as prostate cancer treatment
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- Category: Research
A recombinant Newcastle disease virus kills all kinds of prostate cancer cells, including hormone resistant cells, but leaves normal cells unscathed, according to a paper published online ahead of print in the Journal of Virology. A treatment for prostate cancer based on this virus would avoid the adverse side effects typically associated with hormonal treatment for prostate cancer,
Cortisone can increase risk of acute pancreatitis
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- Category: Research
A new study from Karolinska Institutet in Sweden shows that cortisone - a hormone used in certain medicines - increases the risk of acute pancreatitis. The results are published in the scientific journal JAMA Internal Medicine. According to the researchers, they suggest that patients treated with cortisone in some forms should be informed of the risks and advised to refrain from alcohol and smoking.
Scientists unveil secrets of important natural antibiotic
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- Category: Research
An international team of scientists has discovered how an important natural antibiotic called dermcidin, produced by our skin when we sweat, is a highly efficient tool to fight tuberculosis germs and other dangerous bugs. Their results could contribute to the development of new antibiotics that control multi-resistant bacteria.
Mushroom-supplemented soybean extract shows therapeutic promise for advanced prostate cancer
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- Category: Research
A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found. Men with prostate cancer that has spread to other parts of the body, known as metastatic cancer, and who have had their testosterone lowered with drug therapy are most likely to benefit.
New study on Hepatitis C drug treatment in vivo and in vitro
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- Category: Research
Hepatitis C virus (HCV) infection affects about 4.1 million in the United States and is the primary cause of liver cirrhosis and liver cancer. Current therapy against HCV is suboptimal. Daclatasvir, a direct acting antiviral (DAA) agent in development for the treatment of HCV, targets one of the HCV proteins (i.e., NS5A) and causes the fastest viral decline (within 12 hours of treatment) ever seen with anti-HCV drugs.
Patient-specific cancer cell lines designed to predict chemotherapy sensitivity
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- Category: Research
In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors. If the technique is successful in further studies, it could replace current laboratory tests to optimize drug selection that have proven technically challenging, of limited use, and slow, the researchers say.
Frequently prescribed drug used in concerning ways with harmful side effects
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- Category: Research
Previous studies have linked benzodiazepines - a medication class that may be used in chronic obstructive pulmonary disease (COPD) to treat symptoms of insomnia, depression, anxiety and shortness of breath - with adverse outcomes, but until now there has been little information on how frequently it's prescribed or who is using it.
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