Potential new treatment for gastrointestinal cancers discovered
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- Category: Research
Researchers have identified a complex of proteins that promotes the growth of some types of colon and gastric cancers, and shown that medications that block the function of this complex have the potential to be developed into a new treatment for these diseases.
Study of cancer cell metabolism yields new insights on leukemia
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- Category: Research
University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have a much slower metabolism than most other tumors cells.
Nations that consume a lot of milk... also win a lot of Nobel prizes
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- Category: Research
Nations that consume a lot of milk and milk products also tend to have a lot of Nobel laureates among their populations, suggest the authors of a letter, published in Practical Neurology. Research published last year in the New England Journal of Medicine reported a strong association between a nation's chocolate consumption and Nobel laureate prowess, speculating that the flavonoid content of chocolate was behind the boost in brain power.
Cancer suppressor gene links metabolism with cellular aging
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- Category: Research
It is perhaps impossible to overstate the importance of the tumor suppressor gene p53. It is the single most frequently mutated gene in human tumors. p53 keeps pre-cancerous cells in check by causing cells, among other things, to become senescent - aging at the cellular level. Loss of p53 causes cells to ignore the cellular signals that would normally make mutant or damaged cells die or stop growing.
Spin and bias in published studies of breast cancer trials
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- Category: Research
Spin and bias exist in a high proportion of published studies of the outcomes and adverse side-effects of phase III clinical trials of breast cancer treatments, according to new research published in the cancer journal Annals of Oncology.
Triple mix of blood pressure drugs and painkillers linked to kidney problems
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- Category: Research
Patients who take a triple combination of blood pressure drugs and common painkillers are at an increased risk of serious kidney problems, especially at the start of treatment, finds a study published on British Medical Journal. Although the absolute risk for individuals is low, it is still something doctors and patients should be aware of, say the researchers.
Most-used diabetes drug works in different way than previously thought
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- Category: Research
A team, led by senior author Morris J. Birnbaum, MD, PhD, the Willard and Rhoda Ware Professor of Medicine, with the Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, found that the diabetes drug metformin works in a different way than previously understood.
More Pharma News ...
- Mayo Clinic researchers find new molecule to target in pancreatic cancer treatment
- Experts discover why Rudolph's nose is red
- Gene therapy cocktail shows promise in long-term clinical trial for rare fatal brain disorder
- Mayo Clinic researchers identify enzyme linked to prostate cancer
- New cell-based system can screen drug candidates for cardiac toxicity
- New screening approach identified potential drug combos for difficult-to-treat melanomas
- Study paves way to design drugs aimed at multiple protein targets at once