Reprogrammed cells grow into new blood vessels
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- Category: Research
By transforming human scar cells into blood vessel cells, scientists at Houston Methodist may have discovered a new way to repair damaged tissue. The method, described in an upcoming issue of Circulation, appeared to improve blood flow, oxygenation, and nutrition to areas in need.
Researchers take new approach to stop 'most wanted' cancer protein
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- Category: Research
Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found a way to defeat one of the most tantalizing yet elusive target proteins in cancer cells - employing a strategy that turns the protein's own molecular machinations against it. In a study published online by the journal Cell, the scientists used a specially crafted compound to disrupt the protein's ability to rev up its own production and that of other proteins involved in tumor cell growth.
Best treatments for allergic conditions? Some doctors don't even know
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- Category: Research
People who suffer from allergies want to keep up-to-date on the latest information regarding treatment, but it's not always easy. Some doctors don't even know fact from fiction when it comes to treating allergies. According to a study presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, prevailing allergy myths have a long shelf life.
Cellular extensions with a large effect
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- Category: Research
Tiny extensions on cells, cilia, play an important role in insulin release, according to a new study, which is published in Nature Communications. The researchers report that the cilia of beta cells in the pancreas are covered with insulin receptors and that changed ciliary function can be associated with the development of type 2 diabetes.
NSAIDs prevent colon cancer by inducing death of intestinal stem cells that have mutation
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- Category: Research
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against the development of colorectal cancer by inducing cell suicide pathways in intestinal stem cells that carry a certain mutated and dysfunctional gene, according to a new study led by researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine.
Researchers aim to simplify life saving drug
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- Category: Research
Heparin, the life saving blood thinner used in major surgeries and treatment of heart diseases, is a complicated drug but a research team from the University of British Columbia has set out to make its use a lot safer by developing a universal antidote. Heparin's blood thinning action often requires an antidote to reverse its effect before serious bleeding issues arise especially in the case of major surgical procedures.
Scientists capture picture of 'MicroRNA' in action
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- Category: Research
Biologists at The Scripps Research Institute (TSRI) have described the atomic-level workings of "microRNA" molecules, which control the expression of genes in all animals and plants. The findings add greatly to the understanding of a fundamental system of regulation in biology, and should accelerate the development of therapies that harness its power.
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