Stevia leaf extract has potential as anticancer treatment
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- Category: Research
Stevia may provide more benefits than as a zero-calorie sugar substitute. When fermented with bacteria isolated from banana leaves, stevia extract kills off pancreatic cancer cells but doesn’t harm healthy kidney cells, according to a research team at Hiroshima University.
The researchers published their findings in the International Journal of Molecular Sciences.
Taking the sting out of ulcerative colitis
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- Category: Research
Ulcerative colitis (UC) causes misery for millions worldwide. It affects the large intestine, causing pain, cramping, and frequent bowel movements with bloody diarrhea. Although some people go through periods when they feel well, the disease will suddenly flare up, causing another cycle of pain, diarrhea, and weight loss. There is currently no cure.
Make - your - own weight - loss drug using an innovative genome editing approach
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- Category: Research
Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight - loss drugs, doing away with injections in favor of a one - time treatment.
In a study published in Communications Medicine, researchers from The University of Osaka have revealed that a modified genome editing approach to tackle noncommunicable, multifaceted diseases.
Common autoimmune drug may help reverse immunotherapy - induced diabetes
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- Category: Research
A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor - induced type 1 diabetes, a rare but life-threatening side effect of cancer immunotherapy, using an existing class of autoimmune drugs.
The study, published in JCI Insight, identifies a new group of immune cells involved in the development immune checkpoint inhibitor - induced type 1 diabetes and shows that JAK inhibitors,
Researchers discover new way cells protect themselves from damage
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- Category: Research
An international team led by researchers at The Hospital for Sick Children (SickKids), Princess Margaret Cancer Centre, Dalhousie University, the University of Exeter (UK) and the Medical University of Vienna (Austria) has uncovered a surprising way compartments within cells work together to defend themselves against oxidative stress, a finding that could shift how we understand age-associated conditions such as diabetes and neurodegenerative diseases.
Nerve pain drug gabapentin linked to increased dementia, cognitive impairment risks
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- Category: Research
Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI) - 29% and 85%, respectively - finds a large medical records study published online in the journal Regional Anesthesia & Pain Medicine.
What's more, these risks were more than twice as high in those normally considered too young to develop either condition - 18 - 64 year olds - the findings indicate.
Researchers develop potent CDK9 inhibitor to overcome drug resistance in hematological malignancies
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- Category: Research
A research team led by Prof. LIU Qingsong and Prof. LIU Jing from the Hefei Institutes of Physical Science, Chinese Academy of Sciences, has recently developed a new class of compounds that effectively inhibit both wild-type CDK9 and its drug-resistant mutant form, offering a promising strategy for treating hematological malignancies.
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