While current treatments for schizophrenia - a mental illness affecting 1% of the world’s population - can reduce certain symptoms, they have little effect on the cognitive deficits affecting the daily life of patients.

Scientists at the Institute of Functional Genomics (CNRS/Inserm/Université de Montpellier) have just designed a nanobody made from llama antibodies that can specifically activate a glutamate receptor involved in regulating neural activity.

An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to "wake up" the immune system against cancer.

Published in Nature Biomedical Engineering, the University of Florida study showed that like a one-two punch, pairing the test vaccine with common anticancer drugs called immune checkpoint inhibitors triggered a strong antitumor response.

Chemists have developed a novel way to generate a variety of highly useful chemical building blocks by harnessing metal carbenes, suggests new research.

Typically used in chemical reactions essential for drug synthesis and materials development, carbenes are short-lived, highly reactive carbon atoms.

Stevia may provide more benefits than as a zero-calorie sugar substitute. When fermented with bacteria isolated from banana leaves, stevia extract kills off pancreatic cancer cells but doesn’t harm healthy kidney cells, according to a research team at Hiroshima University.

The researchers published their findings in the International Journal of Molecular Sciences.

Ulcerative colitis (UC) causes misery for millions worldwide. It affects the large intestine, causing pain, cramping, and frequent bowel movements with bloody diarrhea. Although some people go through periods when they feel well, the disease will suddenly flare up, causing another cycle of pain, diarrhea, and weight loss. There is currently no cure.

Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight - loss drugs, doing away with injections in favor of a one - time treatment.

In a study published in Communications Medicine, researchers from The University of Osaka have revealed that a modified genome editing approach to tackle noncommunicable, multifaceted diseases.

A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor - induced type 1 diabetes, a rare but life-threatening side effect of cancer immunotherapy, using an existing class of autoimmune drugs.

The study, published in JCI Insight, identifies a new group of immune cells involved in the development immune checkpoint inhibitor - induced type 1 diabetes and shows that JAK inhibitors,