Triptans more effective than newer, more expensive migraine drugs
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- Category: Research
Triptans work by narrowing blood vessels in the brain and preventing the release of chemicals that cause pain and inflammation.
The findings show that four triptans - eletriptan, rizatriptan, sumatriptan, and zolmitriptan - were better at relieving migraine pain than the recently marketed and more expensive drugs lasmiditan, rimegepant, and ubrogepant, which were comparable to paracetamol and most anti-inflammatory painkillers (NSAIDs).
Up to one-third of antibody drugs are nonspecific
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- Category: Research
More than 39 million deaths from antibiotic-resistant infections estimated between now and 2050
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- Category: Research
The new study by the Global Research on Antimicrobial Resistance (GRAM) Project is the first global analysis of antimicrobial resistance (AMR) trends over time.
It reveals that more than one million people died each year as a result of AMR between 1990 and 2021.
How the immune system fails as cancer arises
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- Category: Research
Studying the behavior of these "pro-tumor" immune cells is important because they could be targets for therapies that block their harmful activity, said Minsoo Kim, PhD, corresponding author of the study and a research leader at the Wilmot Cancer Institute.
Laughter may be as effective as drops for dry eyes
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- Category: Research
The researchers suggest that laughter exercise could be an initial treatment for relieving symptoms of dry eye disease.
Dry eye disease (DED) is a chronic condition estimated to affect around 360 million individuals worldwide.
Gene therapy effective in hereditary blindness
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- Category: Research
Bothnia dystrophy occurs mainly in the region Västerbotten in Sweden, but the disease has also been identified in other parts of the world.
Drugs prescribed off-label may do more harm than good
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- Category: Research
Researchers warn prescribing medicines for a use which it has not been licensed could make things worse, even though the prescriber was trying to help.
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