Generic transplant drugs as good as brand name
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- Category: Research
A University of Cincinnati (UC)-led research team has found that generic formulations of tacrolimus, a drug used post-transplant to lower the risk of organ rejection, are just as good as the name-brand version. The findings were presented Sunday, May 3, by lead investigator Rita Alloway, PharmD, UC research professor of medicine and
Engineering new blood vessels in people is 1 step closer to reality
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- Category: Research
Scientists moved a step closer toward coaxing the body into producing its own replacement blood vessels after discovering that suppressing parts of the innate immune system may raise the chances of a tissue engineered vascular graft's success. In a report appearing in the May 2015 issue of The FASEB Journal scientists showed that
Drug prices to treat multiple sclerosis soar, point to larger problem
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- Category: Research
A new study found that drugs used to treat multiple sclerosis have soared in price in the past two decades, in some cases more than 700 percent, even though newer drugs have come to the market - a process that normally should have stabilized or reduced the cost of at least the older medications.
Inaccurate reporting jeopardizing clinical trials
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- Category: Research
The team led by Dr Sheena Cruickshank of the Faculty of Life Sciences and Professor Andy Brass from the School of Computer Science (University of Manchester) analysed 58 papers on research into inflammatory bowel disease published between 2000 and 2014. They found a wide variety in how methods were reported and that vital information about experiments were missing, meaning they couldn't be accurately reproduced in animal or human models.
Scientists arrange protein-nanoparticle marriage
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- Category: Research
Fastening protein-based medical treatments to nanoparticles isn't easy. With arduous chemistry, scientists can do it. But like a doomed marriage, the fragile binding that holds them together often separates. This problem, which has limited how doctors can use proteins to treat serious disease, may soon change.
Researchers make key malarial drug-resistence finding
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- Category: Research
According to the World Health Organization's 2014 World Malaria Report, there are an estimated 198 million cases of malaria worldwide with 3.3 billion people at risk for contracting the infection. Although the impact of malaria is still significant, the statistics reflect a considerable reduction in the global malaria burden.
Certain genes might make some people more prone to experience the placebo effect
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- Category: Research
Researchers are beginning to explore whether the genetics of patients who experience a placebo effect are different from those of patients who don't. It's well known that people can feel better if they believe they are receiving treatment, but the biological pathways involved are relatively unexplored.
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