Study reveals that chemotherapy works in an unexpected way
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- Category: Research
It's generally thought that anticancer chemotherapies work like antibiotics do, by directly killing off what's harmful. But new research published online on April 4 in the Cell Press journal Immunity shows that effective chemotherapies actually work by mobilizing the body's own immune cells to fight cancer. Researchers found that chemo-treated dying tumors secrete a factor that attracts certain immune cells, which then ingest tumor proteins and present them on their surfaces as alert signals that an invader is present.
New relief for gynecological disorders
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- Category: Research
The creation of new blood vessels in the body, called "angiogenesis," is usually discussed in connection with healing wounds and tumors. But it's also an ongoing process in the female reproductive tract, where the growth and breaking of blood vessels is a normal part of the menstrual cycle. But abnormal growth of blood vessels can have painful consequences and resultant pathologies.
New nanomedicine resolves inflammation, promotes tissue healing
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- Category: Research
A multicenter team of researchers, including scientists at Columbia University Medical Center (CUMC), Brigham and Women's Hospital (BWH), Mount Sinai School of Medicine, and Massachusetts Institute of Technology, has developed biodegradable nanoparticles that are capable of delivering inflammation-resolving drugs to sites of tissue injury.
Newly approved blood thinner may increase susceptibility to some viral infections
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- Category: Research
A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults.
Genetic 'spelling mistakes' that increase the risk of common cancers
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- Category: Research
More than 80 genetic 'spelling mistakes' that can increase the risk of breast, prostate and ovarian cancer have been found in a large, international research study within the framework of the EU Network COGS. For the first time, the researchers also have a relatively clear picture of the total number of genetic alterations that can be linked to these cancers.
T-cell therapy eradicates an aggressive leukemia in 2 children
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Two children with an aggressive form of childhood leukemia had a complete remission of their disease - showing no evidence of cancer cells in their bodies - after treatment with a novel cell therapy that reprogrammed their immune cells to rapidly multiply and destroy leukemia cells. A research team from The Children's Hospital of Philadelphia and the University of Pennsylvania published the case report of two pediatric patients Online First in The New England Journal of Medicine.
Parkinsons' drug helps older people to make decisions
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- Category: Research
A drug widely used to treat Parkinson's Disease can help to reverse age-related impairments in decision making in some older people, a study from researchers at the Wellcome Trust Centre for Neuroimaging has shown. The study, published in the journal Nature Neuroscience, also describes changes in the patterns of brain activity of adults in their seventies that help to explain why they are worse at making decisions than younger people.
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