Pfizer Launches Global Centers for Therapeutic Innovation

Pfizer Inc.Pfizer Inc. (NYSE: PFE) announced the establishment of the Global Centers for Therapeutic Innovation, an entrepreneurial network of partnerships with leading academic medical centers to transform research and development by accessing leading translational researchers. The University of California, San Francisco is the first collaboration in the network.

"The Centers for Therapeutic Innovation represents a truly novel open innovation paradigm, combining the unique advantages of top academic research institutions with Pfizer's leading drug development capabilities and research technologies," said Mikael Dolsten, M.D., Ph.D., president of Pfizer Worldwide Research & Development. "This new way of engaging leading external scientists is a key component of our R&D strategy. We are excited to pioneer this approach to seek to translate science into novel proofs of mechanism in a more efficient and accelerated manner to better serve patients," Dr. Dolsten said.

Anthony Coyle, Ph.D., will head Pfizer's Global Centers for Therapeutic Innovation, headquartered in Cambridge, Mass. Dr. Coyle brings extensive knowledge of the full drug development process to this initiative. As former Vice President and Global Head of Respiratory, Inflammation, and Autoimmune Research at MedImmune Biologics, a division of AstraZeneca, he advanced research and the clinical biologics pipeline.

"With his keen sense of biotechnology culture, strong scientific leadership and history of building successful collaborations, Anthony Coyle is the ideal person to lead the Centers for Therapeutic Innovation," said Jose-Carlos Gutierrez-Ramos, Ph.D., Pfizer's senior vice president of Worldwide BioTherapeutics Research and Development. "This new model complements the venture capitalist - funded biotech start up and has the potential to catalyze the transformation of global biomedical drug discovery by advancing scientific breakthroughs in translational medicine."

A key aspect of the Centers for Therapeutic Innovation is Pfizer's commitment to establish local Centers at each partner site that enable Pfizer and academic medical center teams to work side by side. Pfizer will also make available its proprietary antibody libraries and advanced research tools along with technical support across the development process. In addition to funding pre-clinical and clinical development programs, Pfizer will offer its partners equitable intellectual property and ownership rights to support continued experimentation and exploration, as well as broad rights to publication. Milestone payments and royalties related to the advancement of sponsored programs will also be granted. In return, Pfizer will have the opportunity to potentially broaden its pipeline with novel and highly differentiated candidate drugs to treat diseases of high unmet medical need.

The Centers for Therapeutic Innovation will initially focus on collaborations within the U.S. and build the network at other U.S.-based medical institutions and is expected to expand into Europe and Asia in 2012. Each Center will be governed by a Joint Steering Committee comprised of Pfizer and academic medical center representatives who will provide leadership and evaluate the success of each program through discovery and early stage clinical development.

"This is an excellent example of how we can fundamentally improve the process of translating research into better drugs by bringing all of the people involved to the same table," said Jeffrey A. Bluestone, Ph.D., UCSF executive vice chancellor and provost, and the A.W. and Mary Margaret Clausen Distinguished Professor in Metabolism and Endocrinology at UCSF. "This partnership takes advantage of the expertise in both camps to create new ways to develop drugs that have the potential to achieve their most important goal - improving patient health."

"UCSF is a world-class academic medical center with a strong focus on both basic science and clinical research, which is why Pfizer is partnering with them on this initiative. Ultimately, we believe this could create significant benefit for the patient, for investigators, and for each institution," said Dr. Gutierrez-Ramos.

About the University of California, San Francisco
UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. For further information, visit www.ucsf.edu.

Pfizer Inc.: Working together for a healthier world™
At Pfizer, we apply science and our global resources to improve health and well-being at every stage of life. We strive to set the standard for quality, safety and value in the discovery, development and manufacturing of medicines for people and animals. Our diversified global health care portfolio includes human and animal biologic and small molecule medicines and vaccines, as well as nutritional products and many of the world's best-known consumer products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as the world's leading biopharmaceutical company, we also collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on us. To learn more about our commitments, please visit us at www.pfizer.com.

Most Popular Now

How SARS-CoV-2 mutates to escape antibody binding

In a recurring pattern of evolution, SARS-CoV-2 evades immune responses by selectively deleting small bits of its genetic sequence, according to new research from the Uni...

Anticancer drug may improve outcome for severe COV…

Treating severe COVID-19 patients with the anticancer drug bevacizumab may reduce mortality and speed up recovery, according to a small clinical study in Italy and China ...

Pfizer and BioNTech commence global clinical trial…

Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) announced today that the first participants have been dosed in a global Phase 2/3 study to further evaluate the saf...

One dose of COVID-19 vaccine provokes strong immun…

Although clinical trial data are encouraging, real-world evidence with regard to the COVID-19 vaccine remains scarce. In particular, response to the vaccine among those p...

Johnson & Johnson announces submission of appl…

Johnson & Johnson (NYSE: JNJ) (the Company) announced that Janssen Biotech, Inc., has submitted an application to the U.S. Food and Drug Administration (FDA) requesting E...

GSK and Vir Biotechnology expand coronavirus colla…

GlaxoSmithKline plc (LSE/NYSE: GSK) and Vir Biotechnology, Inc. (Nasdaq: VIR) have signed a binding agreement to expand their existing collaboration to include the resear...

Could a nasal spray prevent coronavirus transmissi…

A nasal antiviral created by researchers at Columbia University Vagelos College of Physicians and Surgeons blocked transmission of SARS-CoV-2 in ferrets, suggesting the n...

European Commission purchases additional 150 milli…

Moderna, Inc. (Nasdaq: MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today announced that the European Commission purchased an...

Neandertal gene variants both increase and decreas…

Last year, researchers at Karolinska Institutet in Sweden and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany showed that a major genetic risk ...

CureVac initiates rolling submission with European…

CureVac N.V. (Nasdaq: CVAC), a global biopharmaceutical company developing a new class of transformative medicines based on messenger ribonucleic acid (mRNA), today annou...

Pfizer and BioNTech publish data from in vitro stu…

Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced the publication in Nature Medicine of data from in vitro studies that demonstrate that sera from in...

Johnson & Johnson Announces Submission to Worl…

Johnson & Johnson (NYSE: JNJ) (the Company) announced that Janssen-Cilag International N.V. has submitted for Emergency Use Listing (EUL) to the World Health Organization...