Development

TB Alliance sublicenses promising anti-tuberculosis drug from the Medicines Patent Pool

On World Tuberculosis Day, TB Alliance and the Medicines Patent Pool (MPP) announced a licensing agreement for the clinical development of sutezolid, an antibiotic drug candidate which demonstrated encouraging results in early studies. The sublicense pertains to the development of sutezolid in combination with other TB drugs and follows the MPP’s license for the treatment signed with patent holder The Johns Hopkins University in January.

Your computer can help scientists search for new childhood cancer treatments

Medical researchers and IBM (NYSE: IBM) are asking the public's help in finding prospective treatments for childhood cancers, the top worldwide cause of death by disease for children. Scientists are searching for chemical drug candidates that can affect the key molecules and proteins that control cancer cells in several common childhood cancers. However, finding drug candidates is an expensive and slow process.

Reshaping the future of global clinical trials practice

Researchers at the University of Liverpool have developed a new international guideline to help standardise how results from clinical trial studies are reported. Use of the COS-STAR guideline, which is published in PLOS Medicine, could increase the efficiency and value of clinical research across the globe.

2016 Nobel Prize in Physiology or Medicine to Yoshinori Ohsumi

The Nobel Assembly at Karolinska Institutet has today decided to award the 2016 Nobel Prize in Physiology or Medicine to Yoshinori Ohsumi for his discoveries of mechanisms for autophagy.

This year's Nobel Laureate discovered and elucidated mechanisms underlying autophagy, a fundamental process for degrading and recycling cellular components.

CHIC Project Survey: Your Opinion Counts

The EU-funded CHIC project (Computational Horizons In Cancer: Developing Meta- and Hyper-Multiscale Models and Repositories for In Silico Oncology) proposes the development of clinical trial driven tools, services and secure infrastructure that will support the creation of multiscale cancer hypermodels (integrative models). The latter are defined as choreographies of component models, each one describing a biological process at a characteristic spatiotemporal scale, and of relation models/metamodels defining the relations across scales.

Global superbug response needs $5bn each year, experts predict

Efforts to tackle drug-resistant infections will require a global fund of at least $5 billion each year, researchers have projected. Experts in infectious diseases are calling for a World Bank Trust Fund to coordinate global action on this growing public health crisis. Growing resistance is leading to the emergence of superbugs that can cause life-threatening infections, such as MRSA or drug-resistant tuberculosis.

Nature publication describes first example of a clinically applicable and systemic mRNA cancer immunotherapy vaccine

BioNTech AG, a fully integrated biotechnology company developing individualized cancer immunotherapies, together with its translational research partner institute TRON, announces a publication in the internationally renowned scientific journal Nature, describing the first example worldwide of a clinically relevant and systemic mRNA cancer immunotherapy.

TB Alliance sublicenses promising anti-tuberculosis drug from the Medicines Patent Pool

Your computer can help scientists search for new childhood cancer treatments

Reshaping the future of global clinical trials practice

2016 Nobel Prize in Physiology or Medicine to Yoshinori Ohsumi

CHIC Project Survey: Your Opinion Counts

Global superbug response needs $5bn each year, experts predict

Nature publication describes first example of a clinically applicable and systemic mRNA cancer immunotherapy vaccine

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