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Sports playbook helps doctors predict cancer patient outcomes

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Research
04 July 2019
In this season of global soccer competitions and hotly contested political primaries, bookies and pundits are scouring every evolving scrap of information and sifting through mountains of data in an effort to predict the outcome of the next game or election. These predictions can change on a dime, however, based on a player's poor pass or a candidate's stellar debate performance.
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New study showing drug prolongs life for patients with ovarian cancer

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Research
02 July 2019
Women with ovarian cancer who have undergone four or more rounds of chemotherapy typically haven't had much hope that another treatment option will lengthen their lives in a meaningful way. However, a new research study shows tremendous promise for a drug called niraparib to extend life when all options have been exhausted.
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Artificial DNA can control release of active ingredients from drugs

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Research
28 June 2019
A drug with three active ingredients that are released in sequence at specific times: Thanks to the work of a team at the Technical University of Munich (TUM), what was once a pharmacologist's dream is now much closer to reality. With a combination of hydrogels and artificial DNA, nanoparticles can be released in sequence under conditions similar to those in the human body.
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How gastric stem cells fight bacteria

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Research
25 June 2019
Stem cells are not only key players in tissue regeneration, they are also capable of taking direct action against bacteria. This is the finding of a study conducted by researchers from Charité - Universitätsmedizin Berlin and the Max Planck Institute for Infection Biology, which describes what happens during a Helicobacter pylori infection of the human stomach. By actively fighting the colonizing bacteria, gastric stem cells protect themselves against damage that can lead to cancer.
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Pathogen engineered to self-destruct underlies cancer vaccine platform

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Research
24 June 2019
A team of investigators has developed a cancer vaccine technology using live, attenuated pathogens as vectors. A feature of the vaccine causes these bacteria to self-destruct once they've done their job, making it safe for use in humans. The research is published in Infection and Immunity, a journal of the American Society for Microbiology.
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Human-on-a-chip model tests cancer drug efficacy and toxicity for therapeutic index

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Research
20 June 2019
A reconfigurable "body-on-a-chip" model could transform drug development by simultaneously measuring compound efficacy and toxicity, for both target cells and other organs, such as the heart and liver. These findings, published in Science Translational Medicine, demonstrate the ability of a body-on-a-chip model to truly revolutionize biomedical research and personalized medicine through more accurate and efficient preclinical testing without the use of animal studies.
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Vitamin D may not help your heart

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Research
19 June 2019
While previous research has suggested a link between low levels of vitamin D in the blood and an increased risk of cardiovascular disease, a new Michigan State University study has found that taking vitamin D supplements did not reduce that risk. The large-scale study, published in the Journal of the American Medical Association Cardiology, found that vitamin D supplements did not decrease the incidence of heart attacks, strokes or other major adverse cardiovascular events.
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More Pharma News ...

  1. Researchers identify enzyme that suppresses immune system in breast cancer
  2. Making it personal: How genetic technologies are changing the face of medicine
  3. Weighing risks and benefits of drug treatment for major depression
  4. Study finds FDA dermatology advisors receive payments following drug approvals
  5. Cleveland researchers test novel gene therapy for glioblastoma
  6. Prescription drug costs steadily soar, yet price transparency is lacking
  7. Cholesterol in eggs tied to cardiac disease, death
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Business & Industry

  • AWS announces strategic collaboration with Novartis to accelerate digital transformation of its business operations
  • AstraZeneca divests rights to Seroquel and Seroquel XR in the US and Canada
  • FDA approves Pfizer's biosimilar, ABRILADA™ (adalimumab-afzb) for multiple inflammatory conditions
  • Imfinzi granted FDA Priority Review for the treatment of patients with extensive-stage small cell lung cancer
  • Bayer selects Pharmaron as partner organization

Research & Development

  • The gut may be involved in the development of multiple sclerosis
  • Olaparib becomes first gene-targeted medicine to show benefits in prostate cancer
  • Investigational drugs reduce risk of death from Ebola virus disease
  • Pharmacist-led interventions may help prevent cardiovascular disease
  • A protein tag to study the immune system
  • Industry executives: Profits drive rising prices for MS drugs
  • Artificial Intelligence algorithm can learn the laws of quantum mechanics and speed up drug delivery

Conferences & Events

  • Excellent market conditions at largest ever CPhI Worldwide bodes well for global pharma in 2020
  • SMi Group's 12th Annual Conference and Exhibition: Pre-Filled Syringes and Injectable Drug Devices 2020
  • SMi's 4th Annual 3D Cell Culture
  • Exploring the dynamics, legalities and hurdles in a period of transition for Parallel Trade
  • RNA Therapeutics Conference and Focus Day
  • CPhI Worldwide announces the winners of the 16th Pharma Awards
  • CPhI Annual Report predicts Europe to surpass the USA in biologic manufacturing capacity by 2023

Regulatory Affairs

  • FDA approves first generics of Gilenya
  • FDA approves novel treatment to target abnormality in sickle cell disease
  • FDA approves first treatment for inherited rare disease
  • FDA approves first targeted therapy to treat patients with painful complication of sickle cell disease
  • FDA approves first therapy to treat patients with rare blood disorder
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