Research & Development News Channel

Combining new and old drugs improves survival for soft-tissue cancer patients

Adding a novel monoclonal antibody therapy to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, a lethal soft-tissue cancer. Findings from a multicenter clinical trial of the combination therapy, led by researchers at Columbia University Medical Center and NewYork-Presbyterian, represent the first appreciable improvement in sarcoma outcomes in decades.

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Anti-tumor antibodies could counter atherosclerosis

Investigators at the Stanford University School of Medicine have learned the signal that tumor cells display on their surfaces to protect themselves from being devoured by the immune system also plays a role in enabling atherosclerosis, the process underlying heart attacks and strokes.

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Moderate exercise might be more effective at combatting pre-diabetes

Walking briskly on a regular basis may be more effective than vigorous jogging for improving glucose control in individuals with pre-diabetes, according to research from Duke Health. The findings, published online July 15 in the journal Diabetologia, are the result of a randomized, six-month study of 150 participants, each of whom was designated as having pre-diabetes based on elevated fasting glucose levels.

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Zika epidemic likely to end within 3 years

The current Zika epidemic in Latin America is likely to burn itself out within three years, suggests new research. The findings, from scientists at Imperial College London, also conclude that the epidemic cannot be contained with existing control measures. The team, who published their findings in the journal Science, predict the next large-scale epidemic is unlikely to emerge for at least another ten years - although there is a possibility of smaller outbreaks in this time.

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Losing weight lowered levels of proteins associated with tumor growth

Overweight or obese women who lost weight through diet or a combination of diet and exercise also significantly lowered levels of proteins in the blood that help certain tumors grow, according to a Fred Hutchinson Cancer Research Center study published July 14 in Cancer Research, a journal of the American Association for Cancer Research.

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Pomegranate finally reveals its powerful anti-aging secret

Are pomegranates really the superfood we've been led to believe will counteract the aging process? Up to now, scientific proof has been fairly weak. And some controversial marketing tactics have led to skepticism as well. A team of scientists from EPFL and the company Amazentis wanted to explore the issue by taking a closer look at the secrets of this plump pink fruit.

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Leukemia drug shows early promise for treating Parkinson's disease and dementia

Parkinson's disease (PD) is the second most common neurodegenerative disorder that causes a range of motor and non-motor symptoms. During the course of the disease, dopamine (DA)-producing neurons are lost and bundles of proteins known as Lewy bodies (LBs) form in the brain.

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AstraZeneca enters licensing agreem…

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Novartis adds bispecific antibodies…

Today Novartis announced that it has entered into a collaboration and licensing agreement with Xencor for the development of bispecific antibodies for treating cancer. Th...

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Bristol-Myers Squibb and PsiOxus Th…

Bristol-Myers Squibb Company (NYSE: BMY) and PsiOxus Therapeutics, Ltd. (PsiOxus) today announced an exclusive clinical collaboration agreement to evaluate the safety, to...

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Bristol-Myers Squibb acquires Cormo…

Bristol-Myers Squibb Company (NYSE:BMY) and Cormorant Pharmaceuticals announced today that Bristol-Myers Squibb has acquired all of the outstanding capital stock of Cormo...

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Sanofi Pasteur signs research agree…

Sanofi and its vaccines global business unit Sanofi Pasteur announced today a Cooperative Research and Development Agreement with the Walter Reed Army Institute of Resear...

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FDA advances Precision Medicine Ini…

In support of the President’s Precision Medicine Initiative, the U.S. Food and Drug Administration has issued two draft guidances that, when finalized, will provide a fle...

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Merck and Pfizer initiate Phase III…

Merck KGaA, Darmstadt, Germany, and Pfizer (NYSE: PFE) have announced the initiation of a Phase III study, JAVELIN Ovarian 100, to evaluate the efficacy and safety of ave...

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Laboratory drug trials could lead t…

A new drug with the potential to reverse or slow the development of asthma is being tested by researchers at The University of Queensland. Developed by international phar...

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