Research & Development News Channel

Only half of patients take their medications as prescribed

Here is what we know: If people take medications prescribed to them, they usually get better. But only about half of all patients prescribed medication take it according to directions. Here is what we don't know: We don't know how to get patients to take their medications, despite many studies looking at the issue.

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Finding new ways to make drugs

Chemists have developed a revolutionary new way to manufacture natural chemicals and used it to assemble a scarce anti-inflammatory drug with potential to treat cancer and malaria. The breakthrough could lead to new and cheaper ways to produce rare drugs in large quantities.

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Reprogramming cells, long term

Harvard Stem Cell Institute (HSCI) researchers, representing five Harvard departments and affiliated institutions as well as the Massachusetts Institute of Technology (MIT), have demonstrated that adult cells, reprogrammed into another cell type in a living animal, can remain functional over a long period.

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Chemical in coffee may help prevent obesity-related disease

Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity. In a paper published recently in Pharmaceutical Research, scientists found that chlorogenic acid, or CGA, significantly reduced insulin resistance and accumulation of fat in the livers of mice who were fed a high-fat diet.

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Single-dose, needle-free Ebola vaccine provides long-term protection in macaques

Scientists have demonstrated for the first time that a single-dose, needleless Ebola vaccine given to primates through their noses and lungs protected them against infection for at least 21 weeks. A vaccine that doesn't require an injection could help prevent passing along infections through unintentional pricks.

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Reprogrammed cells grow into new blood vessels

By transforming human scar cells into blood vessel cells, scientists at Houston Methodist may have discovered a new way to repair damaged tissue. The method, described in an upcoming issue of Circulation, appeared to improve blood flow, oxygenation, and nutrition to areas in need.

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Researchers take new approach to stop 'most wanted' cancer protein

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found a way to defeat one of the most tantalizing yet elusive target proteins in cancer cells - employing a strategy that turns the protein's own molecular machinations against it. In a study published online by the journal Cell, the scientists used a specially crafted compound to disrupt the protein's ability to rev up its own production and that of other proteins involved in tumor cell growth.

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