Updated Pfizer Pipeline Focuses on Value, Unmet Medical Need

Pfizer Inc.Pfizer Inc. (NYSE: PFE) provided an update to its development pipeline, which includes 118 programs from Phase 1 through registration. The updated pipeline continues to reflect Pfizer's ongoing investment in high-priority disease areas with considerable unmet medical need.

"We continue to be confident in the progression of our late-stage pipeline and have advanced three compounds into registration since our last portfolio update," said Ian Read, president of Pfizer's Worldwide Biopharmaceutical Businesses. "We have a strong pipeline with programs in development across important therapeutic areas including oncology, neuroscience and inflammation. We remain committed to growing our biologics and vaccines development programs."

"Building on the rapid integration of Pfizer and Wyeth, the new Pfizer brings a wealth of scientific approaches and technologies to our key investment areas, and we are developing novel product candidates across all phases of development," said Mikael Dolsten, MD, PhD, president of Pfizer's Worldwide Research and Development. "We are leveraging the best product assets of our legacy organizations and driving important steps forward in strategy and method to deliver a portfolio of next generation medicines and vaccines."

Pfizer now has 118 programs in Phase 1 through registration, compared to 133 programs at its last pipeline update in January, 2010. This reflects 25 programs that are new or have advanced along the pipeline and 31 programs that have been discontinued since the last update. The current pipeline includes 26 programs in Phase 3 and nine programs in registration, as well as 27 biologics and four vaccines across all phases of development.

Detailed information about Pfizer's pipeline is available at www.pfizer.com/pipeline. Such information includes an overview of the company's research and a list of compounds in development with targeted indication, phase of development and, for late-stage programs, mechanism of action.

Most Popular Now

Cannabis extract helps reset brain function in psy…

Research from King's College London has found that a single dose of the cannabis extract cannabidiol can help reduce brain function abnormalities seen in people with psyc...

New cancer treatment uses enzymes to boost immune …

Researchers at The University of Texas at Austin have developed a new approach to treating cancer using enzyme therapy. The enzyme, PEG-KYNase, does not directly kill can...

For first time in 40 years, cure for acute leukemi…

Acute myeloid leukemia is one of the most aggressive cancers. While other cancers have benefitted from new treatments, there has been no encouraging news for most leukemi...

Bayer accelerates six new startups

Changing the experience of health: that's the focus of the six startups which the Bayer G4A team has included in the Accelerator program this year. The young companies fr...

Novartis receives European Commission approval of …

Novartis today announced that the European Commission (EC) has approved Kymriah® (tisagenlecleucel, formerly CTL019). The approved indications are for the treatment of pe...

Shire completes sale of oncology franchise

Shire plc (LSE: SHP, NASDAQ: SHPG) announces today that it has completed the sale of its Oncology franchise to Servier S.A.S. for $2.4 billion. The franchise includes the...

Antioxidant reduces risk for second heart attack, …

Doctors have long known that in the months after a heart attack or stroke, patients are more likely to have another attack or stroke. Now, a paper in the Journal of the A...

Novartis to divest the Sandoz US dermatology busin…

Novartis today announced it has agreed to sell selected portions of its Sandoz US portfolio, specifically the Sandoz US dermatology business and generic US oral solids po...

New tablet production facility in Ingelheim: Cente…

Boehringer Ingelheim held a groundbreaking ceremony for the construction of a new production facility for innovative drugs. This new Solids Launch facility will focus on ...

Tezepelumab granted Breakthrough Therapy Designati…

AstraZeneca and its partner Amgen Inc. (Amgen) today announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation for tezepelumab...

Pfizer terminates domagrozumab (PF-06252616) clini…

Pfizer Inc. (NYSE: PFE) announced that it is terminating two ongoing clinical studies evaluating domagrozumab (PF-06252616) for the treatment of Duchenne muscular dystrop...

Pfizer and Astellas amend clinical research protoc…

Pfizer Inc. (NYSE:PFE) and Astellas Pharma Inc. (TSE:4503, President and CEO: Kenji Yasukawa, Ph.D., "Astellas") announced amendments to the protocols for two registratio...