Development

New open access journal highlights methods and clinical trial results

The first issue of Elsevier's new open access journal Contemporary Clinical Trials Communications features a new method to make cancer clinical trials more effective, a better way of determining whether a trial was successful and a dashboard that helps patients enroll in trials. The journal is a spin-off of the well-established title Contemporary Clinical Trials.

There are many ways to carry out a clinical trial. Researchers need to think about the number of patients to enroll, the type of treatments to give and their frequency, among many other factors. Contemporary Clinical Trials Communications publishes methodology and statistics that answer these questions, helping researchers build on each other's work and design better trials.

For example, in the first issue of the journal, which is now available on ScienceDirect, researchers from Genentech Inc. and the Deerfield Institute describe a new trial design that helps researchers take into account delayed effects of immune-oncology treatments.

"I trust that the readers will find the journal a valuable source of recent advancements in clinical trials," said Dr. Zhezhen Jin, co-Editor-in-Chief of Contemporary Clinical Trials Communications and Professor of Biostatistics at Columbia University in New York. He also explained that this knowledge can "facilitate the design, conduct and analysis of their trials."

The journal also aims to tackle the problem of publication bias towards positive results by making all trial data open access.

"A major objective of the journal is to reduce publication bias, which is a major issue in the field of clinical trials," said Dr. Zheng Su, co-Editor-in-Chief of Contemporary Clinical Trials Communications and VP at the Deerfield Institute in New York.

There are two main approaches to clinical trials: randomized and non-randomized. In randomized trials, the participants do not know whether they are receiving the treatment or a placebo. In non-randomized trials, the participants are often all given the treatment. Many clinical trials journals only publish randomized trials, but Contemporary Clinical Trials Communications will publish both.

"There are several existing clinical trials journals that either give preferential treatment to positive trial results due to their perceived higher significance, or focus only on randomized trials," added Dr. Jin. "In contrast, Contemporary Clinical Trials Communications provides a platform for trialists around the world to share their knowledge on all aspects of clinical trials. We're making scientifically valid and technically sound original research findings freely accessible regardless of their perceived importance or impact."

Contemporary Clinical Trials Communications is now open for submissions. The first issue is published on ScienceDirect.

About Contemporary Clinical Trials Communications
Contemporary Clinical Trials Communications is an international, peer-reviewed, open access journal that publishes articles on all aspects of clinical trials, including design, conduct, analysis, regulation and ethics. Articles appeal to a wide range of disciplines. Contemporary Clinical Trials Communications strives to increase the transparency of medical research and reduce publication bias by publishing scientifically valid original research findings, irrespective of their perceived importance, significance or impact.

About Elsevier
Elsevier is a world-leading provider of information solutions that enhance the performance of science, health, and technology professionals, empowering them to make better decisions, deliver better care, and sometimes make groundbreaking discoveries that advance the boundaries of knowledge and human progress. Elsevier provides web-based, digital solutions - among them ScienceDirect, Scopus, Elsevier Research Intelligence and ClinicalKey - and publishes over 2,500 journals, including The Lancet and Cell, and more than 33,000 book titles, including a number of iconic reference works. Elsevier is part of RELX Group plc, a world-leading provider of information solutions for professional customers across industries.

Most Popular Now

AstraZeneca licenses Zurampic to Gr…

AstraZeneca today announced that it has entered into a licensing agreement with Grünenthal GmbH for the exclusive rights to Zurampic (lesinurad) in Europe and Latin Ameri...

Read more

Pfizer presents promising data from…

Pfizer Inc. (NYSE:PFE) today announced encouraging new data from a Phase 1/2 study of lorlatinib, the proposed generic name for PF-06463922, Pfizer's investigational, nex...

Read more

Bayer Science & Education Found…

Applications for the Bayer Science & Education Foundation's international scholarship programs are now being accepted for this year's round. In the academic sector, ambit...

Read more

Merck Accelerator expands its reach…

Merck, a leading science and technology company, has started this week the application period for the next round of its Accelerator programs in Darmstadt, Germany, and Na...

Read more

Call for Abstracts: DIA EuroMeeting…

29 - 31 March 2017, Glasgow, UK. The DIA EuroMeeting 2017 provides a platform for experts from all relevant disciplines within the entire healthcare development and acce...

Read more

AstraZeneca enters commercialisatio…

AstraZeneca today announced it has entered into a commercialisation agreement with Aspen Global Incorporated (AGI), part of the Aspen Group, for rights to its global anae...

Read more

Boehringer Ingelheim and Harvard sc…

Boehringer Ingelheim today announced it has established a research collaboration with the Harvard Stem Cell Institute's - Harvard Fibrosis Network to discover new ways of...

Read more

Merck announces survey results expl…

Merck, a leading science and technology company, today announced survey results of 250 global biopharmaceutical executives on how their companies will manage new risks as...

Read more

FDA targets unlawful internet sales…

The U.S. Food and Drug Administration, in partnership with international regulatory and law enforcement agencies, announced that it took action this week against 4,402 we...

Read more

Promising treatment prospects for i…

In Switzerland alone, more than 5,700 women are diagnosed with breast cancer each year, and almost 1,400 of those affected die of the disease. In many very invasive forms...

Read more

Digital health: A way for pharma co…

Pharmaceutical companies have an opportunity to use their expertise to play a greater role in healthcare reform, while also revamping their business model. We believe t...

Read more

Merck in agreement with HAPPYneuron…

Merck, a leading science and technology company, announced today that the company has entered into an agreement with HAPPYneuron, a subsidiary of SBT Group of France, in ...

Read more

Digest World Pharma Newsletter

Subscribe to our weekly Digest World Pharma Newsletter and stay updated on the latest World Pharma News. Subscribe now, it's free!

Pharmaceutical Companies

[ A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Z ]