Bayer to collaborate with the Children's Hospital & Research Center Oakland to fight rare blood diseases

BayerBayer HealthCare has signed a master collaboration agreement with the California-based Children's Hospital & Research Center Oakland to research hemoglobin disorders, particularly in the area of sickle cell anemia. The agreement aims to utilize promising research approaches to help identify potential new therapies for the rare blood disease.

Scientists based at Bayer HealthCare's U.S. Innovation Center in San Francisco's Mission Bay will work with Children’s Hospital researchers and have formed a joint steering committee to coordinate the research efforts which will be funded by Bayer.

Approximately 5% of the world's population carries trait genes for hemoglobin disorders, mainly sickle cell anemia and thalassemia, according to the World Health Organization. The exact number of people living with sickle cell anemia worldwide or in the U.S. is unknown but the Center for Disease Control estimates sickle cell anemia affects between 90,000 and 100,000 Americans.

"We believe that the expertise of Children’s Hospital researchers' in sickle cell anemia combined with Bayer's expertise in developing therapies for blood diseases will pave the way for innovative research projects that will help improve our understanding in this area and can lead to new treatment options for patients suffering from this rare disease," said Prof. Dr. Andreas Busch, member of the Bayer HealthCare Executive Committee and Head of Global Drug Discovery. "We believe such collaborations between industry and academia can speed up the development of innovative treatments in areas with high unmet medical need."

"Children's Hospital & Research Center Oakland has long been committed to helping this particular patient population and with Bayer's proven expertise in drug development we can help to bring new treatments to the benefit of these patients in a timely manner," said Dr. Elliott Vichinsky, head of the hematology oncology department at Children's Hospital.

As part of the company's overall innovation strategy, Bayer is expanding its collaborative relationships with academia and life science firms all over the world. In the U.S. a dedicated team of scientists at the company's U.S. Innovation Center in San Francisco is charged with identifying and facilitating discovery stage research collaborations for the company.

About sickle cell anemia
Sickle cell anemia is an inherited blood disorder that affects red blood cells. People with sickle cell anemia have a mutation in their hemoglobin gene that results in red blood cells that contain an abnormal type of hemoglobin. Sometimes these red blood cells do not bind oxygen properly, become sickle-shaped and have difficulty passing through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can reach that part of the body. Tissues that do not receive an adequate blood flow eventually suffer damage. This is what causes the complications of sickle cell anemia. The recurrent pain caused by the disease can interfere with many aspects of the patient's social life, including education and employment. There is currently no cure for this rare blood disease. An estimated 100,000 people in the U.S. live with sickle cell anemia and millions are affected globally.

About the Children's Hospital & Research Center Oakland
The Children's Hospital & Research Center Oakland is home to the largest sickle cell and thalassemia program in the western United States. The comprehensive program includes inpatient and outpatient services, and although a pediatric institution also takes care of a growing population of adult patients affected by the diseases. The red blood cell laboratory (www.rbclab.com) at Children's Hospital Research Institute headed by Dr. Frans Kuypers, partners with the hematology department to find new treatment options for sickle cell disease and thalassemia.

About Bayer HealthCare
The Bayer Group is a global enterprise with core competencies in the fields of health care, agriculture and high-tech materials. Bayer HealthCare, a subgroup of Bayer AG with annual sales of EUR 18.6 billion (2012), is one of the world’s leading, innovative companies in the healthcare and medical products industry and is based in Leverkusen, Germany. The company combines the global activities of the Animal Health, Consumer Care, Medical Care and Pharmaceuticals divisions. Bayer HealthCare's aim is to discover, develop, manufacture and market products that will improve human and animal health worldwide. Bayer HealthCare has a global workforce of 55,300 employees (Dec 31, 2012) and is represented in more than 100 countries.

Most Popular Now

Merck invests € 250 million in production value ch…

Merck, a leading science and technology company, today inaugurated its € 170 million Nantong pharmaceutical plant, which is dedicated to producing high-quality pharmaceut...

Read more

Roche launches imCORE, a global network of cancer …

Roche (SIX: RO, ROG; OTCQX: RHHBY) has launched the global cancer immunotherapy Centers of Research Excellence (imCORE™) Network. This network brings together many of the...

Read more

New research shows promise for immunotherapy as HI…

Immunotherapy has revolutionized treatment options in oncology, neurology, and many infectious diseases and now there is fresh hope that the same method could be used to ...

Read more

15th Annual eyeforpharma Philadelphia 2017

20 - 21 April 2017, Philadelphia, USA. It's eyeforpharma Philadelphia's 15th year; already the largest, most senior and most influential forum for commercial pharma exec...

Read more

Pancreatic cancer set to become third biggest canc…

The number of deaths from pancreatic cancer will overtake breast cancer mortality rates in the EU in 2017, a study has found. The findings, recently presented at UEG Week...

Read more

Merck wins R&D 100 Award for top invention

Merck, a leading science and technology company, received a prestigious R&D 100 Award for its Sanger Arrayed Lentiviral CRISPR Libraries - the first of its kind CRISPR li...

Read more

Regorafenib from Bayer submitted to health authori…

Bayer has announced the submission of applications to extend the marketing authorization for its oral multi-kinase inhibitor regorafenib in the U.S., Japan and Europe, fo...

Read more

Researchers discover way to inhibit major cancer g…

Researchers at the University of Illinois at Chicago have identified a new way to block the action of genetic mutations found in nearly 30 percent of all cancers. Mutatio...

Read more

Genetically engineering disease-fighting cells

The human body produces T cells to recognize and fight disease. Each T cell has a unique T cell receptor (or TCR) on its surface that surveils small fragments of proteins...

Read more

New European study highlights differing priorities…

Results from a survey analysing the prescribing behaviour of 500 European physicians treating patients with advanced non-small cell lung cancer (NSCLC) have been publishe...

Read more

Benzodiazepine and related drug use increases hip …

The use of benzodiazepines and related drugs increases the risk of hip fracture by 43% in persons with Alzheimer's disease, according to a new study from the University o...

Read more

Among antidementia drugs, memantine is associated …

A recent study from the University of Eastern Finland shows that among users of antidementia drugs, persons using memantine have the highest risk of pneumonia. The use of...

Read more

Pharmaceutical Companies

[ A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Z ]