The SGC and Boehringer Ingelheim will work together on different research projects aimed at identifying small molecules that can enhance or inhibit the activity of proteins involved in epigenetic control. The study of epigenetics addresses heritable changes in gene function that occur without a change in the DNA sequence. Alterations in these processes are linked to many common diseases such as cancer, diabetes, inflammation, obesity and several psychiatric diseases. The discovery of new chemical probes is hoped to contribute to dramatic increases in our understanding of these processes and some of these probes may also provide starting points for drug discovery.
"We are excited about being able to join the SGC", said Dr. Adrian Carter, Corporate Vice President of Global Research Networking of Boehringer Ingelheim. He added, "this is a unique opportunity to work on unprecedented science in a precompetitive public-private partnership with a large global scientific network . We hope that it will help us in starting new drug discovery programs in areas of high unmet medical need".
About The Structural Genomics Consortium (SGC)
Located at the Universities of Toronto and Oxford, the not-for-profit organization supports the discovery of new medicines by carrying open access research in structural and chemical biology. More than 200 researchers in academia and in eight pharmaceutical companies collaborate within SGC to accomplish these goals. The SGC is also funded by the Canadian Institutes for Health Research, CFI, Genome Canada, the Ontario's MEDI, and the Wellcome Trust.
About Boehringer Ingelheim
The Boehringer Ingelheim group is one of the world's 20 leading pharmaceutical companies. Headquartered in Ingelheim, Germany, it operates globally with 140 affiliates and more than 46,000 employees. Since it was founded in 1885, the family-owned company has been committed to researching, developing, manufacturing and marketing novel medications of high therapeutic value for human and veterinary medicine.
As a central element of its culture, Boehringer Ingelheim pledges to act socially responsible. Involvement in social projects, caring for employees and their families, and providing equal opportunities for all employees form the foundation of the global operations. Mutual cooperation and respect, as well as environmental protection and sustainability are intrinsic factors in all of Boehringer Ingelheim's endeavors.
In 2012, Boehringer Ingelheim achieved net sales of about 14.7 billion euros. R&D expenditure in the business area Prescription Medicines corresponds to 22.5% of its net sales.